Substitution at R3 that has a halogen or alkoxy group (74f–74i) brought about a slight rise in mobile potency Using the halide analogs (74g–h) showing highest the potency during the group. Even further optimization brought about the discovery of 74i–j, with 74k as quite possibly the most active compound in https://israeljcrfv.blogdeazar.com/31583869/indazole-derivatives-things-to-know-before-you-buy