It's not necessarily mandatory, having said that it is recommended for getting vaccinated to fight yellow fever (minimum 10 times right after arrival) In these aspects of the Amazon there won't be any land roadways o entry the jungle, most transportation is by motor boat. Boat excursion over the Madre https://puertomaldonadotours95937.ambien-blog.com/38072668/the-best-side-of-puerto-maldonado-tours