The discordance between pre-clinical success and clinical failure of treatment options for Duchenne Muscular Dystrophy (DMD) is significant. The termination of clinical trials investigating the phosphodiesterase inhibitors. sildenafil and tadalafil (which prolong the second messenger molecule of nitric oxide (NO) signaling). are prime examples of this. https://www.bekindtopets.com/hot-find-Synovex-One-Grass-Extended-Release-Implant-10-Dose-special-find/