Pentobarbital will decrease the level or effect of losartan by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of levoketoconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. Acting as both a sedative and a hypnotic, pentobarbital can be prescribed for the short-term tr... https://barbaraf322ulc0.dgbloggers.com/profile